How Sequence Complexity Algorithms Shape DNA Design
July 1, 2025
Learn how complexity algorithms like Shannon entropy and Kolmogorov complexity improve DNA design, manufacturability, and reduce synthesis failures. ...
Casey-Tyler Berezin
DNA Synthesis in 2025: Technologies, Trends, and Tips
June 24, 2025
Explore how DNA and gene synthesis work, from phosphoramidite to enzymatic methods, with 2025 provider insights and design tips for successful constructs. ...
DNA Design Tools: From Plasmid Maps to Codon Optimization
June 19, 2025
Optimize the DNA design process with tools for plasmid mapping, codon optimization, gene annotation, and in silico simulation to streamline synthesis workflows. ...
Promoter and RBS Selection for Gene Expression
June 9, 2025
Learn how promoter and RBS selection impacts gene expression in plasmid design. Optimize transcription and translation for better experimental outcomes. ...
Top 5 Common Mistakes in Plasmid Design (And How to Avoid Them)
June 5, 2025
Avoid the most common plasmid design mistakes with tips for optimizing expression, stability, and reproducibility. Design smarter from the start. ...
How Plasmid Host Systems Shape Sequence Design
May 29, 2025
Discover how plasmid design differs across plasmid host systems like bacteria, yeast, and mammalian cells. Learn key components, design tips, and challenges. ...
Choosing the best origin of replication
May 22, 2025
Learn how to choose the best origin of replication to control plasmid stability, copy number, and performance across bacterial, yeast, and mammalian systems. High copy...
What is a plasmid?
May 4, 2025
Learn what plasmids are, how they work, and the mistakes to avoid. A practical guide for life scientists designing experiments with plasmids. ...
Jean Peccoud
Codon optimization
November 29, 2024
Codon optimization is the process of modifying a gene's DNA sequence to use codons preferred by the host organism, without changing the amino acid sequence,...
Kozak Sequences
November 19, 2024
The Kozak sequence is a specific nucleotide sequence in eukaryotic messenger RNA (mRNA) that plays a critical role in the initiation of translation. It helps...
