Endotoxin Testing & Control in Plasmid Manufacturing
July 24, 2025
Learn how endotoxin testing, LAL assays, and downstream purification ensure plasmids meet regulatory standards for research and therapeutic use, and the interesting role of horseshoe...
Casey-Tyler Berezin
Lab Automation for DNA Workflows: Robots to Results
July 16, 2025
Lab automation using robotics, liquid handlers, and colony pickers streamlines DNA workflows for faster, more reliable plasmid production. ...
How Sequence Complexity Algorithms Shape DNA Design
July 1, 2025
Learn how complexity algorithms like Shannon entropy and Kolmogorov complexity improve DNA design, manufacturability, and reduce synthesis failures. ...
DNA Synthesis in 2025: Technologies, Trends, and Tips
June 24, 2025
Explore how DNA and gene synthesis work, from phosphoramidite to enzymatic methods, with 2025 provider insights and design tips for successful constructs. ...
DNA Design Tools: From Plasmid Maps to Codon Optimization
June 19, 2025
Optimize the DNA design process with tools for plasmid mapping, codon optimization, gene annotation, and in silico simulation to streamline synthesis workflows. ...
Modern DNA Cloning Techniques for Modular Assembly
June 13, 2025
Explore molecular cloning techniques like restriction cloning, Gibson assembly, and Golden Gate assembly. Learn how modular assembly improves scalability and flexibility. ...
Promoter and RBS Selection for Gene Expression
June 9, 2025
Learn how promoter and RBS selection impacts gene expression in plasmid design. Optimize transcription and translation for better experimental outcomes. ...
Top 5 Common Mistakes in Plasmid Design (And How to Avoid Them)
June 5, 2025
Avoid the most common plasmid design mistakes with tips for optimizing expression, stability, and reproducibility. Design smarter from the start. ...
Plasmid Types and Their Applications
June 2, 2025
Learn how plasmid types like cloning, expression, shuttle, reporter, viral vectors, and artificial chromosomes support diverse molecular biology research goals. ...
How Plasmid Host Systems Shape Sequence Design
May 29, 2025
Discover how plasmid design differs across plasmid host systems like bacteria, yeast, and mammalian cells. Learn key components, design tips, and challenges. ...
Choosing the right selectable marker
May 24, 2025
Highlights Plasmids need selectable markers to isolate successful transformants. Marker type affects plasmid size, host burden, and regulatory risks. Antibiotic resistance genes are common but...
Choosing the best origin of replication
May 22, 2025
Learn how to choose the best origin of replication to control plasmid stability, copy number, and performance across bacterial, yeast, and mammalian systems. High copy...
